Spandex fetishism is a fetishistic attraction to people wearing shiny stretch fabrics or, in certain cases, to the garments themselves.

Many people refer to spandex fetishism as Lycra fetishism, although Lycra is INVISTA's trademark for their own brand of spandex fabric.

One reason why spandex and other tight fabrics may be fetishised is that the garment forms a "second skin," acting as a fetishistic surrogate for the wearer's own skin. Wearers of skin-tight spandex garments can appear naked or coated in a shiny substance like paint. The tightness of the garments may also be seen as sexual bondage.

Spandex is often produced in bright colors.

Spandex fetishism often involves dressing up in the material, or looking at it worn by sexual partners, or fantasies about wearers of skin-tight spandex garments such as athletes, acrobats, gymnasts, dancers, swimmers and contortionists.

In comic books, superheroes, superheroines, and supervillains are generally depicted as wearing costumes made of spandex or a similar material. Fantasies involving superheroes or the wearing of superhero costumes are commonly associated with spandex fetishism. This type of fetishism is usually restricted to men. In superheroine-fetishistic pornography, the superheroines, who are either dressed up as either canonical characters or characters invented solely for the fetish, are typically in some sort of trouble, such as bound or fighting supervillains (who are usually also female). The superheroines always wear skintight, very flashy and bright-colored costumes that usually cover only just enough of the female body to be presentable.

Full-body suits called zentai entirely immerse the wearer in skin tight fabric. The suits are essentially catsuits with gloves, feet, and a hood. The wearer gets to experience total enclosure and those who enjoy erotic objectification might make use of the garment's anonymizing aspect. Zentai fetishism appears to be quite popular in Japan and Europe.

Kigurumi, a form of Japanese costuming, often makes use of lyrca as artificial skin.